Highest impact structures: Difference between revisions
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m →Highest Impact Macromolecular Structures of All Time: added 2012 Nobel prize in Chemistry |
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* '''2000 - [[Ribosome]]''': This structure surprised almost everyone by showing that peptidyl transferase is a ribozyme, rather than a protein enzyme. It won the [[Nobel_Prizes_for_3D_Molecular_Structure#Twenty-First_Century|2009 Nobel Prize in Chemistry]]. | * '''2000 - [[Ribosome]]''': This structure surprised almost everyone by showing that peptidyl transferase is a ribozyme, rather than a protein enzyme. It won the [[Nobel_Prizes_for_3D_Molecular_Structure#Twenty-First_Century|2009 Nobel Prize in Chemistry]]. | ||
* | * '''2007 and 2011 - [[G protein-coupled receptor]]''': In 2007 the structure of the first ligand-activated G protein-coupled receptor and in 2011 the first activated G protein-coupled receptor bound to its G protein. This is a large class of proteins that have great importance as targets for drug development; it is estimated that 4% of the human genome devoted to protein coding encodes this class of proteins. The determination of the structures lead to Brian Kobilika sharing the [[Nobel_Prizes_for_3D_Molecular_Structure#Twenty-First_Century|2012 Nobel Prize in Chemistry]] | ||
==Structures Saving The Most Lives== | ==Structures Saving The Most Lives== | ||
