Sandbox 39: Difference between revisions
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=Structure= | =Structure= | ||
ADK is a protein made up of 214 amino acids. The <scene name='Sandbox_39/Adenylate_kinase_main_chain2/1'>mainchain</scene> of adenylate kinase can be seen here in purple. The <scene name='Sandbox_39/Adenylate_kinase_beta_sheets2/1'>secondary | ADK is a protein made up of 214 amino acids. The <scene name='Sandbox_39/Adenylate_kinase_main_chain2/1'>mainchain</scene> of adenylate kinase can be seen here in purple. The <scene name='Sandbox_39/Adenylate_kinase_beta_sheets2/1'>secondary structure</scene> contains 12 alpha helices (light blue) and 7 beta sheets (yellow). The <scene name='Sandbox_39/Adenylate_kinase_hbonds2/1'>backbone Hydrogen bonds</scene> hold the protein together. | ||
<scene name='Sandbox_39/Adenylate_kinase_hydro_resid3/1'>Hydrophobic Residues</scene> | <scene name='Sandbox_39/Adenylate_kinase_hydro_resid3/1'>Hydrophobic Residues</scene> | ||
Revision as of 03:42, 18 October 2012
Please do NOT make changes to this Sandbox. Sandboxes 30-60 are reserved for use by Biochemistry 410 & 412 at Messiah College taught by Dr. Hannah Tims during Fall 2012 and Spring 2013.
DescriptionAdenylate kinase, commonly known as ADK, is a phosphotransferase enzyme. It has two important roles in the body. First, ADK plays an important role in nucleotide metabolism in many organisms. It also has a role in cellular energetics and homeostasis by phosphotransfer networks. Adenylate kinase catalyzes the reaction that forms ADP. The reaction is ATP + AMP = 2 ADP. In this catalyzed reaction, ADK molecules bind to AMP molecules and increase its binding affinity for ATP over other phosphate groups. However, adenylate kinase is also found in other molecules such as bacteria and yeast. ADK plays similar roles in bacteria and yeast, in that it involves cellular metabolism and energy. The following images highlight the structure of Adenylate kinase from Yersinia pestis. StructureADK is a protein made up of 214 amino acids. The mainchain of adenylate kinase can be seen here in purple. The secondary structure contains 12 alpha helices (light blue) and 7 beta sheets (yellow). The backbone Hydrogen bonds hold the protein together.
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