Sandbox 50: Difference between revisions

The active site, like mentioned above, is where the ligand/substrate binds to the enzyme to be catalyzed. In ADK, the <scene name='Sandbox_50/Ak_ligand_contact1/1'>ligand_contacts</scene> (gray, blue, pink), is in the interior of the protein. The pink is where the ligand binds directly, and where it would form hydrogen bonds with the nearby residues, so it is stabilized in the active site. There are also six <scene name='Sandbox_50/Ak_catalytic_residues1/1'>catalytic_residues</scene>, which are specifically involved in the catalyzes of the substrates, and they are highlighted black on the image. They are all charged residues and include Lysine, Aspartic acid, and Arginine.