Sandbox 33: Difference between revisions

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==Enzyme Activity==

The active site is where the substrate binds to the enzyme to be catalyzed. The ligand binds to the <scene name='Sandbox_33/Ligand_contacts/1'>ligand contacts</scene> (depicted in color) of the protein. There are mostly ~~HYDROPHILIC RESIDUES~~ in the active site because water enter the active site. There are also some ~~HYDROPHOBIC RESIDUES~~ in the active site, which interacts with the hydrophobic portions of the substrate (or more likely, the transition state) to stabilize it during catalysis. There are ~~SIX~~ <scene name='Sandbox_33/Catalytic_residues/1'>catalytic residues</scene> ~~CHECK TO SEE IF RIGHT ONES~~ (which are highlighted in blue while all the ligand contacts are depicted in pink) which help perform the catalysis by forming hydrogen bonds with the substrate to hold it in place for the reaction.

The active site is where the substrate binds to the enzyme to be catalyzed. The ligand binds to the <scene name='Sandbox_33/Ligand_contacts/1'>ligand contacts</scene> (depicted in color) of the protein. There are mostly hydrophilic residues in the active site because water enter the active site. There are also some hydrophobic residues in the active site, which interacts with the hydrophobic portions of the substrate (or more likely, the transition state) to stabilize it during catalysis. There are six <scene name='Sandbox_33/Catalytic_residues/1'>catalytic residues</scene> (which are highlighted in blue while all the ligand contacts are depicted in pink) which help perform the catalysis by forming hydrogen bonds with the substrate to hold it in place for the reaction.

==Resources==

http://en.wikipedia.org/wiki/Adenylate_kinase

Sandbox 33: Difference between revisions

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@@ Line 23: / Line 23: @@
 ==Enzyme Activity==
-The active site is where the substrate binds to the enzyme to be catalyzed. The ligand binds to the <scene name='Sandbox_33/Ligand_contacts/1'>ligand contacts</scene> (depicted in color) of the protein.  There are mostly HYDROPHILIC RESIDUES in the active site because water enter the active site.  There are also some HYDROPHOBIC RESIDUES in the active site, which interacts with the hydrophobic portions of the substrate (or more likely, the transition state) to stabilize it during catalysis.  There are SIX <scene name='Sandbox_33/Catalytic_residues/1'>catalytic residues</scene>  CHECK TO SEE IF RIGHT ONES (which are highlighted in blue while all the ligand contacts are depicted in pink) which help perform the catalysis by forming hydrogen bonds with the substrate to hold it in place for the reaction.
+The active site is where the substrate binds to the enzyme to be catalyzed. The ligand binds to the <scene name='Sandbox_33/Ligand_contacts/1'>ligand contacts</scene> (depicted in color) of the protein.  There are mostly hydrophilic residues in the active site because water enter the active site.  There are also some hydrophobic residues in the active site, which interacts with the hydrophobic portions of the substrate (or more likely, the transition state) to stabilize it during catalysis.  There are six <scene name='Sandbox_33/Catalytic_residues/1'>catalytic residues</scene> (which are highlighted in blue while all the ligand contacts are depicted in pink) which help perform the catalysis by forming hydrogen bonds with the substrate to hold it in place for the reaction.
 ==Resources==
 http://en.wikipedia.org/wiki/Adenylate_kinase