3km4: Difference between revisions
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[[Image:3km4.png|left|200px]] | |||
[[Image:3km4. | |||
{{STRUCTURE_3km4| PDB=3km4 | SCENE= }} | {{STRUCTURE_3km4| PDB=3km4 | SCENE= }} | ||
===Optimization of Orally Bioavailable Alkyl Amine Renin Inhibitors=== | ===Optimization of Orally Bioavailable Alkyl Amine Renin Inhibitors=== | ||
{{ABSTRACT_PUBMED_19959358}} | {{ABSTRACT_PUBMED_19959358}} | ||
==About this Structure== | ==About this Structure== | ||
[[3km4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KM4 OCA]. | |||
==See Also== | |||
*[[Renin|Renin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019959358</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
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[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydrolase | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Hypertension]] | [[Category: Hypertension]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
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[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 07:55, 20 October 2012
Optimization of Orally Bioavailable Alkyl Amine Renin Inhibitors
Template:ABSTRACT PUBMED 19959358
About this Structure
3km4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Xu Z, Cacatian S, Yuan J, Simpson RD, Jia L, Zhao W, Tice CM, Flaherty PT, Guo J, Ishchenko A, Singh SB, Wu Z, McKeever BM, Scott BB, Bukhtiyarov Y, Berbaum J, Mason J, Panemangalore R, Cappiello MG, Bentley R, Doe CP, Harrison RK, McGeehan GM, Dillard LW, Baldwin JJ, Claremon DA. Optimization of orally bioavailable alkyl amine renin inhibitors. Bioorg Med Chem Lett. 2010 Jan 15;20(2):694-9. Epub 2009 Dec 1. PMID:19959358 doi:10.1016/j.bmcl.2009.11.066
