3i81: Difference between revisions

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{{Seed}}
[[Image:3i81.png|left|200px]]
[[Image:3i81.jpg|left|200px]]


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{{STRUCTURE_3i81|  PDB=3i81  |  SCENE=  }}  
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===Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with BMS-754807 [1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoro-3-pyridinyl)-2-methyl-L-prolinamide]===
===Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with BMS-754807 [1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoro-3-pyridinyl)-2-methyl-L-prolinamide]===


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{{ABSTRACT_PUBMED_19778024}}
{{ABSTRACT_PUBMED_19778024}}


==Disease==
==About this Structure==
Known disease associated with this structure: Insulin-like growth factor I, resistance to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147370 147370]]
[[3i81]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I81 OCA].


==About this Structure==
==See Also==
3I81 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I81 OCA].
*[[Insulin-like growth factor receptor|Insulin-like growth factor receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:19778024</ref><references group="xtra"/>
<ref group="xtra">PMID:019778024</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Disulfide bond]]
[[Category: Disulfide bond]]
[[Category: Hormone]]
[[Category: Hormone/growth factor]]
[[Category: Hormone/growth factor]]
[[Category: Igf-1r]]
[[Category: Igf-1r]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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