3gyn: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3gyn]] is a 2 chain structure | [[3gyn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYN OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 08:48, 20 October 2012
Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydropyridinone inhibitor
Template:ABSTRACT PUBMED 19796938
About this Structure
3gyn is a 2 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.
See Also
Reference
- Ellis DA, Blazel JK, Tran CV, Ruebsam F, Murphy DE, Li LS, Zhao J, Zhou Y, McGuire HM, Xiang AX, Webber SE, Zhao Q, Han Q, Kissinger CR, Lardy M, Gobbi A, Showalter RE, Shah AM, Tsan M, Patel RA, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6047-52. Epub 2009 Sep 17. PMID:19796938 doi:10.1016/j.bmcl.2009.09.051
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Categories:
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- RNA-directed RNA polymerase
- Viruses
- Han, Q.
- Kissinger, C R.
- Showalter, R E.
- Zhao, Q.
- Apoptosis
- Atp-binding
- Capsid protein
- Cell membrane
- Disulfide bond
- Endoplasmic reticulum
- Envelope protein
- Fusion protein
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- Helicase
- Host-virus interaction
- Hydrolase
- Interferon antiviral system evasion
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- Mitochondrion
- Multifunctional enzyme
- Nucleotide-binding
- Nucleotidyltransferase
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- Palmitate
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- Ribonucleoprotein
- Rna replication
- Rna-binding
- Rna-directed rna polymerase
- Secreted
- Serine protease
- Sh3-binding
- Thiol protease
- Transcription
- Transcription regulation
- Transferase
- Transmembrane
- Viral nucleoprotein
- Virion
