1ls8: Difference between revisions
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New page: left|200px<br /><applet load="1ls8" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ls8" /> '''NMR structure of the unliganded Bombyx mori ... |
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[[Image:1ls8.gif|left|200px]]<br /><applet load="1ls8" size=" | [[Image:1ls8.gif|left|200px]]<br /><applet load="1ls8" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1ls8" /> | caption="1ls8" /> | ||
'''NMR structure of the unliganded Bombyx mori pheromone-binding protein at physiological pH'''<br /> | '''NMR structure of the unliganded Bombyx mori pheromone-binding protein at physiological pH'''<br /> | ||
==Overview== | ==Overview== | ||
The nuclear magnetic resonance structure of the unliganded | The nuclear magnetic resonance structure of the unliganded pheromone-binding protein (PBP) from Bombyx mori at pH above 6.5, BmPBP(B), consists of seven helices with residues 3-8, 16-22, 29-32, 46-59, 70-79, 84-100, and 107-124, and contains the three disulfide bridges 19-54, 50-108, and 97-117. This polypeptide fold encloses a large hydrophobic cavity, with a sufficient volume to accommodate the natural ligand bombykol. The polypeptide folds in free BmPBP(B) and in crystals of a BmPBP-bombykol complex are nearly identical, indicating that the B-form of BmPBP in solution represents the active conformation for ligand binding. | ||
==About this Structure== | ==About this Structure== | ||
1LS8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http:// | 1LS8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LS8 OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Guntert, P.]] | [[Category: Guntert, P.]] | ||
[[Category: Horst, R.]] | [[Category: Horst, R.]] | ||
[[Category: Leal, W | [[Category: Leal, W S.]] | ||
[[Category: Lee, D.]] | [[Category: Lee, D.]] | ||
[[Category: Wuthrich, K.]] | [[Category: Wuthrich, K.]] | ||
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[[Category: solution structure]] | [[Category: solution structure]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:47:56 2008'' | ||
