2fdp: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[2fdp]] is a 3 chain structure | [[2fdp]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDP OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 09:37, 20 October 2012
Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor
Template:ABSTRACT PUBMED 16451048
About this Structure
2fdp is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yang W, Lu W, Lu Y, Zhong M, Sun J, Thomas AE, Wilkinson JM, Fucini RV, Lam M, Randal M, Shi XP, Jacobs JW, McDowell RS, Gordon EM, Ballinger MD. Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1. J Med Chem. 2006 Feb 9;49(3):839-42. PMID:16451048 doi:10.1021/jm0509142