2va6: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[2va6]] is a 1 chain structure | [[2va6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VA6 OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 10:19, 20 October 2012
X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 24
Template:ABSTRACT PUBMED 17985862
About this Structure
2va6 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Edwards PD, Albert JS, Sylvester M, Aharony D, Andisik D, Callaghan O, Campbell JB, Carr RA, Chessari G, Congreve M, Frederickson M, Folmer RH, Geschwindner S, Koether G, Kolmodin K, Krumrine J, Mauger RC, Murray CW, Olsson LL, Patel S, Spear N, Tian G. Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency. J Med Chem. 2007 Nov 29;50(24):5912-25. Epub 2007 Nov 7. PMID:17985862 doi:https://dx.doi.org/10.1021/jm070829p
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Aharony, D.
- Albert, J S.
- Andisik, D.
- Callaghan, O.
- Campbell, J B.
- Carr, R A.
- Chessari, G.
- Congreve, M.
- Edwards, P D.
- Folmer, R H.A.
- Frederickson, M.
- Geschwindner, S.
- Koether, G.
- Kolmodin, K.
- Krumrine, J.
- Mauger, R C.
- Murray, C W.
- Olsson, L L.
- Patel, S.
- Spear, N.
- Sylvester, M.
- Tian, G.
- Alzheimer's disease
- Aspartic protease
- Aspartyl protease
- Base
- Beta-secretase
- Glycoprotein
- Hydrolase
- Membrane
- Protease
- Transmembrane
- Zymogen
