2wip: Difference between revisions

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==About this Structure==
==About this Structure==
[[2wip]] is a 4 chain structure of [[Cell Division Protein Kinase 2]] and [[Cyclin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIP OCA].  
[[2wip]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WIP OCA].  


==See Also==
==See Also==
Line 16: Line 16:
==Reference==
==Reference==
<ref group="xtra">PMID:019603809</ref><references group="xtra"/>
<ref group="xtra">PMID:019603809</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Amboldi, N.]]
[[Category: Amboldi, N.]]

Revision as of 11:12, 20 October 2012

File:2wip.png

Template:STRUCTURE 2wip

STRUCTURE OF CDK2-CYCLIN A COMPLEXED WITH 8-ANILINO-1-METHYL-4,5-DIHYDRO- 1H-PYRAZOLO[4,3-H] QUINAZOLINE-3-CARBOXYLIC ACID

Template:ABSTRACT PUBMED 19603809

About this Structure

2wip is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Brasca MG, Amboldi N, Ballinari D, Cameron A, Casale E, Cervi G, Colombo M, Colotta F, Croci V, D'Alessio R, Fiorentini F, Isacchi A, Mercurio C, Moretti W, Panzeri A, Pastori W, Pevarello P, Quartieri F, Roletto F, Traquandi G, Vianello P, Vulpetti A, Ciomei M. Identification of N,1,4,4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydr o-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (PHA-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor. J Med Chem. 2009 Jul 15. PMID:19603809 doi:10.1021/jm9006559

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