3fl0: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3fl0]] is a 2 chain structure | [[3fl0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FL0 OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 12:48, 20 October 2012
X-ray structure of the non covalent swapped form of the Q28L/K31C/S32C mutant of bovine pancreatic ribonuclease in complex with 2'-DEOXYCYTIDINE-2'-DEOXYGUANOSINE-3',5'-MONOPHOSPHATE
Template:ABSTRACT PUBMED 19280639
About this Structure
3fl0 is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
See Also
Reference
- Merlino A, Krauss IR, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F. Towards an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three non-covalent dimeric mutants. Biopolymers. 2009 Mar 11. PMID:19280639 doi:10.1002/bip.21183
- Sica F, Di Fiore A, Merlino A, Mazzarella L. Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease: an enzyme tailored to evade ribonuclease protein inhibitor. J Biol Chem. 2004 Aug 27;279(35):36753-60. Epub 2004 Jun 9. PMID:15192098 doi:https://dx.doi.org/10.1074/jbc.M405655200
- Merlino A, Ercole C, Picone D, Pizzo E, Mazzarella L, Sica F. The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme. J Mol Biol. 2008 Feb 15;376(2):427-37. Epub 2007 Nov 12. PMID:18164315 doi:https://dx.doi.org/10.1016/j.jmb.2007.11.008
- Di Donato A, Cafaro V, Romeo I, D'Alessio G. Hints on the evolutionary design of a dimeric RNase with special bioactions. Protein Sci. 1995 Aug;4(8):1470-7. PMID:8520472 doi:https://dx.doi.org/10.1002/pro.5560040804
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Bos taurus
- Pancreatic ribonuclease
- Ercole, C.
- Krauss, I Russo.
- Mattia, C A.
- Merlino, A.
- Perillo, M.
- Picone, D.
- Sica, F.
- Vergara, A.
- 3d-domain swapping
- Antitumor activity
- Bovine seminal ribonuclease
- Endonuclease
- Glycation
- Glycoprotein
- Hydrolase
- Non-covalent dimer
- Nuclease
- Protein mutations and evolution
- Quaternary structure flexibility
- Secreted