2zm1: Difference between revisions

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==About this Structure==
==About this Structure==
[[2zm1]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] and [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZM1 OCA].  
[[2zm1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZM1 OCA].  


==See Also==
==See Also==

Revision as of 13:23, 20 October 2012

File:2zm1.png

Template:STRUCTURE 2zm1

Crystal structure of imidazo pyrazin 1 bound to the kinase domain of human LCK, (auto-phosphorylated on TYR394)

Template:ABSTRACT PUBMED 18977146

About this Structure

2zm1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Ozawa T, Tsuji E, Ozawa M, Handa C, Mukaiyama H, Nishimura T, Kobayashi S, Okazaki K. The importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase. Bioorg Med Chem. 2008 Dec 15;16(24):10311-8. Epub 2008 Oct 22. PMID:18977146 doi:10.1016/j.bmc.2008.10.041

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