3f5p: Difference between revisions

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[[Image:3f5p.png|left|200px]]
[[Image:3f5p.png|left|200px]]


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{{STRUCTURE_3f5p|  PDB=3f5p  |  SCENE=  }}  
{{STRUCTURE_3f5p|  PDB=3f5p  |  SCENE=  }}  


===Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor===
===Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor===


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{{ABSTRACT_PUBMED_19041240}}
{{ABSTRACT_PUBMED_19041240}}


==About this Structure==
==About this Structure==
[[3f5p]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F5P OCA].  
[[3f5p]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F5P OCA].  
==See Also==
*[[Insulin-like growth factor receptor|Insulin-like growth factor receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:19041240</ref><ref group="xtra">PMID:18501599</ref><references group="xtra"/>
<ref group="xtra">PMID:019041240</ref><ref group="xtra">PMID:018501599</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
[[Category: Receptor]]
[[Category: Receptor]]

Revision as of 13:44, 20 October 2012

File:3f5p.png

Template:STRUCTURE 3f5p

Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor

Template:ABSTRACT PUBMED 19041240

About this Structure

3f5p is a 16 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Miller LM, Mayer SC, Berger DM, Boschelli DH, Boschelli F, Di L, Du X, Dutia M, Floyd MB, Johnson M, Kenny CH, Krishnamurthy G, Moy F, Petusky S, Tkach D, Torres N, Wu B, Xu W. Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment. Bioorg Med Chem Lett. 2009 Jan 1;19(1):62-6. Epub 2008 Nov 17. PMID:19041240 doi:S0960-894X(08)01390-5
  2. Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W. Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. Epub 2008 Apr 25. PMID:18501599 doi:10.1016/j.bmcl.2008.04.044

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