3rkz: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3rkz]] is a 1 chain structure | [[3rkz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RKZ OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 19:33, 20 October 2012
Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor capable of significantly decreasing tumor volume in a mouse xenograft model.
Template:ABSTRACT PUBMED 21715165
About this Structure
3rkz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zapf CW, Bloom JD, Li Z, Dushin RG, Nittoli T, Otteng M, Nikitenko A, Golas JM, Liu H, Lucas J, Boschelli F, Vogan E, Olland A, Johnson M, Levin JI. Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model. Bioorg Med Chem Lett. 2011 Jun 27. PMID:21715165 doi:10.1016/j.bmcl.2011.05.102
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Categories:
- Pages with broken file links
- Homo sapiens
- Bloom, J D.
- Boschelli, F.
- Dushin, R G.
- Golas, J M.
- Johnson, M.
- Levin, J I.
- Li, Z.
- Liu, H.
- Lucas, J.
- Nikitenko, A.
- Nittoli, T.
- Olland, A.
- Otteng, M.
- Vogan, E.
- Zapf, C W.
- Atp binding domain
- Atp-binding
- Chaperone
- Chaperone-chaperone inhibitor complex
- Nucleotide-binding
- Phosphoprotein
- Stress response