1oit: Difference between revisions
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==Overview== | ==Overview== | ||
High-throughput screening identified the imidazo[1,2-a]pyridine and | High-throughput screening identified the imidazo[1,2-a]pyridine and bisanilinopyrimidine series as inhibitors of the cyclin-dependent kinase CDK4. Comparison of their experimentally-determined binding modes and emerging structure-activity trends led to the development of potent and selective imidazo[1,2-a]pyridine inhibitors for CDK4 and in particular CDK2. | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Transferred entry: 2 | [[Category: Transferred entry: 2 7.11 1]] | ||
[[Category: Beattie, J | [[Category: Beattie, J F.]] | ||
[[Category: Breault, G | [[Category: Breault, G A.]] | ||
[[Category: Byth, K | [[Category: Byth, K F.]] | ||
[[Category: Culshaw, J | [[Category: Culshaw, J D.]] | ||
[[Category: Ellston, R | [[Category: Ellston, R P.A.]] | ||
[[Category: Green, S.]] | [[Category: Green, S.]] | ||
[[Category: Jewsbury, P | [[Category: Jewsbury, P J.]] | ||
[[Category: Minshull, C | [[Category: Minshull, C A.]] | ||
[[Category: Norman, R | [[Category: Norman, R A.]] | ||
[[Category: Pauptit, R | [[Category: Pauptit, R A.]] | ||
[[Category: Thomas, A | [[Category: Thomas, A P.]] | ||
[[Category: HDT]] | [[Category: HDT]] | ||
[[Category: protein kinase]] | [[Category: protein kinase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:18:14 2008'' | ||
