Sandbox 43: Difference between revisions
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<Structure load='1AKE' size='500' frame='true' align='right' caption='Adenylate kinase' scene='Scene 1' /> | <Structure load='1AKE' size='500' frame='true' align='right' caption='Adenylate kinase' scene='Scene 1' /> | ||
==Introduction== | ==Introduction== | ||
<scene name='Sandbox_43/Samaniego_scene/1'>Adenylate kinase</scene> is an enzyme | <scene name='Sandbox_43/Samaniego_scene/1'>Adenylate kinase</scene> is an enzyme that catalyzes the reversible reaction in which a molecule of ATP and a molecule of AMP are converted into two molecules of ADP through the following reaction scheme: | ||
ATP + AMP ⇔ 2 ADP | ATP + AMP ⇔ 2 ADP | ||
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==Ligand Interactions== | ==Ligand Interactions== | ||
Portions of adenylate kinase which interact with the ligand are shown here in purple. These are called the <scene name='Sandbox_43/Samaniego_scene_ligand2/1'>ligand contacts</scene> and have polar-charged side chains, which help to stabilize the ligand as it binds to the protein's active site. The catalytic resides (unable to be pictured) are able to directly interact/bind to the ligand. | Portions of adenylate kinase which interact with the ligand are shown here in purple. These are called the <scene name='Sandbox_43/Samaniego_scene_ligand2/1'>ligand contacts</scene> and have polar-charged side chains, which help to stabilize the ligand as it binds to the protein's active site. The catalytic resides (unable to be pictured) are able to directly interact/bind to the ligand. | ||
==Sources== | |||
Library CHEM410 page: http://libguides.messiah.edu/content.php?pid=279182&sid=2407875 | |||
Wikipedia: http://en.wikipedia.org/wiki/Adenylate_kinase | |||
European Bioinformatics Institute: http://www.ebi.ac.uk/interpro/IEntry?ac=IPR000850 | |||
