Integrin: Difference between revisions
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<StructureSection load='1zoo' size='400' side='right' caption='Structure of human integrein CD11a I domain dimer complex with Mg+2 (light green) and Cl- (dark green) ions (PDB entry [[1zoo]])' scene=''> | <StructureSection load='1zoo' size='400' side='right' caption='Structure of human integrein CD11a I domain dimer complex with Mg+2 (light green) and Cl- (dark green) ions (PDB entry [[1zoo]])' scene=''> | ||
'''Integrins''' (IG) are receptors which mediate the attachment between cells or to extracellular matrix. They are involved in cellular signaling and cell cycle. IGs contain | '''Integrins''' (IG) are receptors which mediate the attachment between cells or to extracellular matrix. They are involved in cellular signaling and cell cycle. IGs contain α and β chain. IG subunits span the cell membrane. Both subunits bind divalent cations some of which bind the ligands which interact with IG. Some IGs contain an insertion domain named I domain. | ||
==3D structures of integrin== | ==3D structures of integrin== | ||
