Sandbox Reserved 640: Difference between revisions
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Because Leghemoglobin can autooxidize, there are several mechanisms to maintain the protein in its active (reduced) form. One of them involves an enzyme called, Leghemogobin Reductase. This protein is a flavoprotein that catalyzes the reduction of Lb<sup>3+</sup> (ferric form) to Lb<sup>2+</sup> (ferrous form) using NADH. The reaction is as follows: | Because Leghemoglobin can autooxidize, there are several mechanisms to maintain the protein in its active (reduced) form. One of them involves an enzyme called, Leghemogobin Reductase. This protein is a flavoprotein that catalyzes the reduction of Lb<sup>3+</sup> (ferric form) to Lb<sup>2+</sup> (ferrous form) using NADH. The reaction is as follows: | ||
<div style="text-align: center;"> NAD(P)H + H+ + 2 ferrileghemoglobin NAD(P)+ + 2 ferroleghemoglobin </div> | <div style="text-align: center;"> NAD(P)H + H+ + 2 ferrileghemoglobin NAD(P)+ + 2 ferroleghemoglobin </div> | ||
Ferric Leghemoglobin can also be reduced to the ferrous form by free flavins in the presence of NADH or NADPH. Lastly, Leghemoglobin can be reduced to its ferrous form directly by physiological reductants. These reductants are various electron donors commonly found in plant cells, which reduce the Leghemoglobin nonenzymatically. | Ferric Leghemoglobin can also be reduced to the ferrous form by free flavins in the presence of NADH or NADPH. Lastly, Leghemoglobin can be reduced to its ferrous form directly by physiological reductants. These reductants are various electron donors commonly found in plant cells, which reduce the Leghemoglobin nonenzymatically. | ||
