1ekx: Difference between revisions

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{{Seed}}
[[Image:1ekx.png|left|200px]]
[[Image:1ekx.png|left|200px]]


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{{STRUCTURE_1ekx|  PDB=1ekx  |  SCENE=  }}  
{{STRUCTURE_1ekx|  PDB=1ekx  |  SCENE=  }}  


===THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE)===
===THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE)===


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{{ABSTRACT_PUBMED_10805770}}


==About this Structure==
==About this Structure==
1EKX is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EKX OCA].  
[[1ekx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EKX OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:10805770</ref><references group="xtra"/>
<ref group="xtra">PMID:010805770</ref><ref group="xtra">PMID:015731101</ref><ref group="xtra">PMID:020681545</ref><references group="xtra"/>
[[Category: Aspartate carbamoyltransferase]]
[[Category: Aspartate carbamoyltransferase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Atcase catalytic subunit]]
[[Category: Atcase catalytic subunit]]
[[Category: Bisubstrate analog complex]]
[[Category: Bisubstrate analog complex]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:36:25 2009''

Revision as of 14:43, 8 November 2012

File:1ekx.png

Template:STRUCTURE 1ekx

THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE)

About this Structure

1ekx is a 3 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Endrizzi JA, Beernink PT, Alber T, Schachman HK. Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5077-82. PMID:10805770 doi:10.1073/pnas.090087197
  2. Shi D, Morizono H, Yu X, Roth L, Caldovic L, Allewell NM, Malamy MH, Tuchman M. Crystal structure of N-acetylornithine transcarbamylase from Xanthomonas campestris: a novel enzyme in a new arginine biosynthetic pathway found in several eubacteria. J Biol Chem. 2005 Apr 15;280(15):14366-9. Epub 2005 Feb 24. PMID:15731101 doi:10.1074/jbc.C500005200
  3. Mendes KR, Kantrowitz ER. A cooperative Escherichia coli aspartate transcarbamoylase without regulatory subunits . Biochemistry. 2010 Sep 7;49(35):7694-703. PMID:20681545 doi:10.1021/bi1010333

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