1ex8: Difference between revisions
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Revision as of 07:28, 14 November 2012
CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE COMPLEXED WITH HP4A, THE TWO-SUBSTRATE-MIMICKING INHIBITOR
About this Structure
1ex8 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Shi G, Blaszczyk J, Ji X, Yan H. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies. J Med Chem. 2001 Apr 26;44(9):1364-71. PMID:11311059
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
- Escherichia coli
- Blaszczyk, J.
- Ji, X.
- Active-site architecture
- Antimicrobial agent
- Bisubstrate-mimicking inhibitor
- Drug design
- Folate
- Hppk
- Pterin
- Pyrophosphokinase
- Pyrophosphoryl transfer
- Substrate specificity
- Transferase
