Saposin: Difference between revisions

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{{STRUCTURE_1n69|  PDB=1n69 | SIZE=400| SCENE= |right|CAPTION=Human saposin C complex with lipid molecule, [[1n69]] }}
{{STRUCTURE_2dob|  PDB=2dob | SIZE=400| SCENE= |right|CAPTION=Human saposin C complex with lipid molecule, [[2dob]] }}


'''Saposin''' (Sap) is a small protein which functions as activator of lipid-degrading enzymes.  They act by isolating the lipid substrate from the membrane.  Sap is synthesized as a precursor – prosaposin – which contain 4 SapB active domains and 2 SapA domains which are cleaved off.  For more details see [[Molecular Playground/Saposin C]].
'''Saposin''' (Sap) is a small protein which functions as activator of lipid-degrading enzymes.  They act by isolating the lipid substrate from the membrane.  Sap is synthesized as a precursor – prosaposin – which contain 4 SapB active domains and 2 SapA domains which are cleaved off.  For more details see [[Molecular Playground/Saposin C]].