2ykm: Difference between revisions

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[[Image:2ykm.png|left|200px]]
[[Image:2ykm.png|left|200px]]


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===CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH A DIFLUOROMETHYLBENZOXAZOLE (DFMB) PYRIMIDINE THIOETHER DERIVATIVE, A NON-NUCLEOSIDE RT INHIBITOR (NNRTI)===
===Crystal structure of HIV-1 Reverse Transcriptase (RT) in complex with a Difluoromethylbenzoxazole (DFMB) Pyrimidine Thioether derivative, a non-nucleoside RT inhibitor (NNRTI)===


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Revision as of 09:52, 21 November 2012

File:2ykm.png

Template:STRUCTURE 2ykm

Crystal structure of HIV-1 Reverse Transcriptase (RT) in complex with a Difluoromethylbenzoxazole (DFMB) Pyrimidine Thioether derivative, a non-nucleoside RT inhibitor (NNRTI)

Template:ABSTRACT PUBMED 22017513

About this Structure

2ykm is a 2 chain structure with sequence from Human immunodeficiency virus type 1 bh10. Full crystallographic information is available from OCA.

Reference

  1. Boyer J, Arnoult E, Medebielle M, Guillemont J, Unge J, Jochmans D. Difluoromethylbenzoxazole Pyrimidine Thioether Derivatives: A Novel Class of Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. J Med Chem. 2011 Dec 8;54(23):7974-85. Epub 2011 Nov 4. PMID:22017513 doi:10.1021/jm200766b

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