4acd: Difference between revisions

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[[Image:4acd.jpg|left|200px]]
[[Image:4acd.png|left|200px]]


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{{STRUCTURE_4acd|  PDB=4acd  |  SCENE=  }}  
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===GSK3b in complex with inhibitor===
===GSK3b in complex with inhibitor===


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{{ABSTRACT_PUBMED_22489897}}
{{ABSTRACT_PUBMED_22489897}}


Revision as of 09:52, 21 November 2012

File:4acd.png

Template:STRUCTURE 4acd

GSK3b in complex with inhibitor

Template:ABSTRACT PUBMED 22489897

About this Structure

4acd is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Berg S, Bergh M, Hellberg S, Hogdin K, Lo-Alfredsson Y, Soderman P, von Berg S, Weigelt T, Ormo M, Xue Y, Tucker J, Neelissen J, Jerning E, Nilsson Y, Bhat R. Discovery of Novel Potent and Highly Selective Glycogen Synthase Kinase-3beta (GSK3beta) Inhibitors for Alzheimer's Disease: Design, Synthesis, and Characterization of Pyrazines. J Med Chem. 2012 Apr 27. PMID:22489897 doi:10.1021/jm201724m

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