Sandbox Reserved 653: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 19: | Line 19: | ||
'''Mechanism of Structure:''' | '''Mechanism of Structure:''' | ||
Aspartate (Asp) + α-ketoglutarate ⇌ oxaloacetate + glutamate (Glu) | |||
'''Implications of Possible Actions:''' | '''Implications of Possible Actions:''' | ||
Asparatate Aminotransferase is found in the liver, heart, muscles, kidneys, and other organs. When any of these organs are damaged AST is released and this results in elevated levels of the enzyme in serum. These levels parallel the severity of damage within the organ. Increases in AST levels are common after Heart attack, muscle injury, and Liver disease. In some cases pregnancy can decrease AST levels.Liver damage is commonly detected through a liver function panel which measures the levels of both AST and Alanine Aminotransferase (ALT). When levels of AST exceed the levels of ALT this indicates that the liver disease is most likely alcohol-induced damager, liver tumors, or cirrhosis. When such damage occurs AST levels can take three to six months to return to normal levels. | |||
'''References:''' | '''References:''' | ||
