1rii: Difference between revisions
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New page: left|200px<br /><applet load="1rii" size="450" color="white" frame="true" align="right" spinBox="true" caption="1rii, resolution 1.70Å" /> '''Crystal structure of... |
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[[Image:1rii.gif|left|200px]]<br /><applet load="1rii" size=" | [[Image:1rii.gif|left|200px]]<br /><applet load="1rii" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1rii, resolution 1.70Å" /> | caption="1rii, resolution 1.70Å" /> | ||
'''Crystal structure of phosphoglycerate mutase from M. Tuberculosis'''<br /> | '''Crystal structure of phosphoglycerate mutase from M. Tuberculosis'''<br /> | ||
==Overview== | ==Overview== | ||
The single-crystal X-ray structure of phosphoglycerate mutase from | The single-crystal X-ray structure of phosphoglycerate mutase from Mycobacterium tuberculosis has been determined at a resolution of 1.70 angstroms. The C-terminal tail of each of the subunits is flexible and disordered; however, for one of the four chains (chain A) all but five residues of the chain could be modeled. Noteworthy features of the structure include the active site and a proline-rich segment in each monomer forming a short left-handed polyprolyl helix. These segments lie on the enzyme surface and could conceivably participate in protein-protein interactions. | ||
==About this Structure== | ==About this Structure== | ||
1RII is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with GOL as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Phosphoglycerate_mutase Phosphoglycerate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.1 5.4.2.1] Full crystallographic information is available from [http:// | 1RII is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Phosphoglycerate_mutase Phosphoglycerate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.1 5.4.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RII OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Pashkova, I.]] | [[Category: Pashkova, I.]] | ||
[[Category: Perry, J.]] | [[Category: Perry, J.]] | ||
[[Category: Sawaya, M | [[Category: Sawaya, M R.]] | ||
[[Category: TBSGC, TB | [[Category: TBSGC, TB Structural Genomics Consortium.]] | ||
[[Category: Wu, Y.]] | [[Category: Wu, Y.]] | ||
[[Category: GOL]] | [[Category: GOL]] | ||
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[[Category: tbsgc]] | [[Category: tbsgc]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:51:15 2008'' | ||
