1ris: Difference between revisions

[[Image:1ris.jpg|left|200px]]<br /><applet load="1ris" size="350" color="white" frame="true" align="right" spinBox="true"  

The amino acid sequence and crystal structure of the ribosomal protein S6 from the small ribosomal subunit of Thermus thermophilus have been determined. S6 is a small protein with 101 amino acid residues. The 3D structure, which was determined to 2.0 A resolution, consists of a four-stranded anti-parallel beta-sheet with two alpha-helices packed on one side. Similar folding patterns have been observed for other ribosomal proteins and may suggest an original RNA-interacting motif. Related topologies are also found in several other nucleic acid-interacting proteins and based on the assumption that the structure of the ribosome was established early in the molecular evolution, the possibility that an ancestral RNA-interacting motif in ribosomal proteins is the evolutionary origin for the nucleic acid-interacting domain in large classes of ribonucleic acid binding proteins should be considered.

1RIS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RIS OCA].  

[[Category: Eliseikina, I A.]]

[[Category: Fomenkova, N P.]]

[[Category: Garber, M B.]]

[[Category: Muranova, T A.]]

[[Category: Nikonov, S V.]]

[[Category: Rykonova, A I.]]

[[Category: Sedelnikova, S E.]]

[[Category: Svensson, L A.]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:51:22 2008''