1o5e: Difference between revisions

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{{Seed}}
[[Image:1o5e.png|left|200px]]
[[Image:1o5e.png|left|200px]]


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{{STRUCTURE_1o5e|  PDB=1o5e  |  SCENE=  }}  
{{STRUCTURE_1o5e|  PDB=1o5e  |  SCENE=  }}  


===Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)===
===Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)===


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{{ABSTRACT_PUBMED_15522303}}
{{ABSTRACT_PUBMED_15522303}}


==About this Structure==
==About this Structure==
1O5E is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O5E OCA].  
[[1o5e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O5E OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15522303</ref><references group="xtra"/>
<ref group="xtra">PMID:015522303</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chan, H.]]
[[Category: Chan, H.]]
Line 43: Line 31:
[[Category: Factor viia]]
[[Category: Factor viia]]
[[Category: Hepsin]]
[[Category: Hepsin]]
[[Category: Hydrolase]]
[[Category: S1 site]]
[[Category: S1 site]]
[[Category: Scavenger receptor cysteine-rich domain]]
[[Category: Scavenger receptor cysteine-rich domain]]
[[Category: Selectivity]]
[[Category: Selectivity]]
[[Category: Serine protease]]
[[Category: Serine protease ala190 upa]]
[[Category: Serine protease ala190 upa]]
[[Category: Srcr]]
[[Category: Srcr]]
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Trypsin]]
[[Category: Trypsin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:11:38 2009''

Revision as of 20:52, 5 December 2012

File:1o5e.png

Template:STRUCTURE 1o5e

Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)

Template:ABSTRACT PUBMED 15522303

About this Structure

1o5e is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Katz BA, Luong C, Ho JD, Somoza JR, Gjerstad E, Tang J, Williams SR, Verner E, Mackman RL, Young WB, Sprengeler PA, Chan H, Mortara K, Janc JW, McGrath ME. Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA). J Mol Biol. 2004 Nov 19;344(2):527-47. PMID:15522303 doi:10.1016/j.jmb.2004.09.032

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