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HIV proteases are essential for the functioning of the retrovirus that causes AIDS. HIV needs active proteases to process Gag & Gap - Polymerase polyprotein precursors into mature structural proteins and replicative enzymes.  
HIV proteases are essential for the functioning of the retrovirus that causes AIDS. HIV needs active proteases to process Gag & Gap - Polymerase polyprotein precursors into mature structural proteins and replicative enzymes.  
HIV proteases contain a highly conserved region Asp - Thr - Gly (Asp25, Thr26 and Gly27), with the aspartic residue beeing the active site in the aspartyl protease.(1)
HIV proteases contain a highly conserved region Asp - Thr - Gly (Asp25, Thr26 and Gly27), with the aspartic residue beeing the active site in the aspartyl protease.[[(1)]]


== '''Activity''' ==
== '''Activity''' ==