Sandbox Reserved 717: Difference between revisions
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In the gp12 there are two molecules of SO4 ligands. One of them <scene name='Sandbox_Reserved_717/Mynewscene/19'>SO4 (1529)</scene> interacts with the citric acid. The blue molecule is the SO4. The other <scene name='Sandbox_Reserved_717/Mynewscene/21'>SO4 molecule (1530) interacts with Ser387</scene> . It builds two hydrogen bounds to Ser287 with the distances 2.66 and 3.20. | In the gp12 there are two molecules of SO4 ligands. One of them <scene name='Sandbox_Reserved_717/Mynewscene/19'>SO4 (1529)</scene> interacts with the citric acid. The blue molecule is the SO4. The other <scene name='Sandbox_Reserved_717/Mynewscene/21'>SO4 molecule (1530) interacts with Ser387</scene> . It builds two hydrogen bounds to Ser287 with the distances 2.66 and 3.20. | ||
Click here to see the hydrogen bounds: | Click here to see the hydrogen bounds: *[http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=1ocy&template=ligands.html&l=2.2] | ||
*[http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=1ocy&template=ligands.html&l=2.2] | |||
=== '''Citric Acid''' === | === '''Citric Acid''' === | ||
The <scene name='Sandbox_Reserved_717/Mynewscene/19'>citric acid </scene>. It is drawn in green. The citric acid interacts with following amino acids: Arg465 (distance 3.01), Asp455(distance 2.42) and Tyr454 (distance2.94). Here you can see the interactions:<scene name='Sandbox_Reserved_717/Mynewscene/22'>Interaction between citric acid, SO4, Asp465, Asp455 and Tyr454</scene>. These interactions are caused by hydrogen bounds. | The <scene name='Sandbox_Reserved_717/Mynewscene/19'>citric acid </scene>. It is drawn in green. The citric acid interacts with following amino acids: Arg465 (distance 3.01), Asp455(distance 2.42) and Tyr454 (distance2.94). Here you can see the interactions:<scene name='Sandbox_Reserved_717/Mynewscene/22'>Interaction between citric acid, SO4, Asp465, Asp455 and Tyr454</scene>. These interactions are caused by hydrogen bounds. | ||
Click here to see the interactians between the citric acid, SO4 and the amino acids: | Click here to see the interactians between the citric acid, SO4 and the amino acids: *[http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=1ocy&template=ligands.html&l=1.1] | ||
*[http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=1ocy&template=ligands.html&l=1.1] | |||
=== '''Zinc''' === | === '''Zinc''' === | ||
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The role of the zinc ion is probably absolute of structural nature. It increases the stability of the C-terminus of gp12 against proteases, but it also raises the stability of the C-terminus in general. | The role of the zinc ion is probably absolute of structural nature. It increases the stability of the C-terminus of gp12 against proteases, but it also raises the stability of the C-terminus in general. | ||
Click here to see the interaction between the zinc ion and the two His amino acids: | Click here to see the interaction between the zinc ion and the two His amino acids: *[http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=1ocy&template=ligands.html&o=METAL&l=1.1] | ||
*[http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl?pdbcode=1ocy&template=ligands.html&o=METAL&l=1.1] | |||
== '''Applications''' == | == '''Applications''' == | ||
