TAL effector: Difference between revisions
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‘HD’ RVDs: | ‘HD’ RVDs: | ||
the aspartate residue makes [http://en.wikipedia.org/wiki/Van_der_Waals_force van der Waals] contacts with the edge of the corresponding cytosine base and a hydrogen bond to the cytosine N4 atom. | the aspartate residue makes [http://en.wikipedia.org/wiki/Van_der_Waals_force van der Waals] contacts with the edge of the corresponding cytosine base and a [http://en.wikipedia.org/wiki/Hydrogen_bond hydrogen bond] to the cytosine N4 atom. | ||
‘NG’ and | ‘NG’ and ‘HG’ RVDs: | ||
make a contact in which the backbone alpha carbon of the glycine residue forms a nonpolar van der Waals interaction with the methyl group of the opposing thymine base (average distance ~ 3.3 Å). At the one position where an NG is aligned opposite a cytosine base, the backbone carbonyl and alpha-carbon of the same glycine residue displays a less favorable, far more distant contact (~ 6 Å). | make a contact in which the backbone alpha carbon of the glycine residue forms a nonpolar van der Waals interaction with the methyl group of the opposing thymine base (average distance ~ 3.3 Å). At the one position where an NG is aligned opposite a cytosine base, the backbone carbonyl and alpha-carbon of the same glycine residue displays a less favorable, far more distant contact (~ 6 Å). | ||
