1s8o: Difference between revisions

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{{Seed}}
[[Image:1s8o.png|left|200px]]
[[Image:1s8o.png|left|200px]]


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{{STRUCTURE_1s8o|  PDB=1s8o  |  SCENE=  }}  
{{STRUCTURE_1s8o|  PDB=1s8o  |  SCENE=  }}  


===Human soluble Epoxide Hydrolase===
===Human soluble Epoxide Hydrolase===


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{{ABSTRACT_PUBMED_15096040}}
{{ABSTRACT_PUBMED_15096040}}
==Disease==
Known disease associated with this structure: Hypercholesterolemia, familial, due to LDLR defect, modifier of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=132811 132811]]


==About this Structure==
==About this Structure==
1S8O is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S8O OCA].  
[[1s8o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S8O OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15096040</ref><references group="xtra"/>
<ref group="xtra">PMID:015096040</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Microsomal epoxide hydrolase]]
[[Category: Hydrolase]]
[[Category: Christianson, D W.]]
[[Category: Christianson, D W.]]
[[Category: Gomez, G A.]]
[[Category: Gomez, G A.]]
Line 34: Line 19:
[[Category: Morisseau, C.]]
[[Category: Morisseau, C.]]
[[Category: Domain-swapped dimer]]
[[Category: Domain-swapped dimer]]
 
[[Category: Hydrolase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:11:30 2009''

Revision as of 09:57, 4 January 2013

File:1s8o.png


Drag the structure with the mouse to rotate
1s8o, resolution 2.60Å (default scene)
Ligands: P6G
Gene: EPHX2 (Homo sapiens)
Activity: Hydrolase, with EC number and 3.3.2.10 3.3.2.9 and 3.3.2.10
Related: 1vj5
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Human soluble Epoxide Hydrolase

Template:ABSTRACT PUBMED 15096040

About this Structure

1s8o is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Gomez GA, Morisseau C, Hammock BD, Christianson DW. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochemistry. 2004 Apr 27;43(16):4716-23. PMID:15096040 doi:10.1021/bi036189j

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