1s0z: Difference between revisions
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[[Image:1s0z.png|left|200px]] | [[Image:1s0z.png|left|200px]] | ||
{{STRUCTURE_1s0z| PDB=1s0z | SCENE= }} | {{STRUCTURE_1s0z| PDB=1s0z | SCENE= }} | ||
===Crystal structure of the VDR LBD complexed to seocalcitol.=== | ===Crystal structure of the VDR LBD complexed to seocalcitol.=== | ||
{{ABSTRACT_PUBMED_15055995}} | {{ABSTRACT_PUBMED_15055995}} | ||
==About this Structure== | ==About this Structure== | ||
[[1s0z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S0Z OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:015055995</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Moras, D.]] | [[Category: Moras, D.]] | ||
| Line 30: | Line 18: | ||
[[Category: Wurtz, J M.]] | [[Category: Wurtz, J M.]] | ||
[[Category: Alpha-helical sandwich]] | [[Category: Alpha-helical sandwich]] | ||
[[Category: Gene regulation]] | |||
[[Category: Nuclear receptor]] | [[Category: Nuclear receptor]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
Revision as of 10:05, 4 January 2013
Crystal structure of the VDR LBD complexed to seocalcitol.
Template:ABSTRACT PUBMED 15055995
About this Structure
1s0z is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Tocchini-Valentini G, Rochel N, Wurtz JM, Moras D. Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification. J Med Chem. 2004 Apr 8;47(8):1956-61. PMID:15055995 doi:10.1021/jm0310582