1s64: Difference between revisions

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{{Seed}}
[[Image:1s64.png|left|200px]]
[[Image:1s64.png|left|200px]]


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{{STRUCTURE_1s64|  PDB=1s64  |  SCENE=  }}  
{{STRUCTURE_1s64|  PDB=1s64  |  SCENE=  }}  


===Rat protein geranylgeranyltransferase type-I complexed with L-778,123 and a sulfate anion===
===Rat protein geranylgeranyltransferase type-I complexed with L-778,123 and a sulfate anion===


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{{ABSTRACT_PUBMED_15248757}}
{{ABSTRACT_PUBMED_15248757}}


==About this Structure==
==About this Structure==
1S64 is a 12 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S64 OCA].  
[[1s64]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S64 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15248757</ref><references group="xtra"/>
<ref group="xtra">PMID:015248757</ref><references group="xtra"/>
[[Category: Protein geranylgeranyltransferase type I]]
[[Category: Protein geranylgeranyltransferase type I]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
Line 29: Line 17:
[[Category: Long, S B.]]
[[Category: Long, S B.]]
[[Category: Reid, T S.]]
[[Category: Reid, T S.]]
[[Category: 123]]
[[Category: Drug]]
[[Category: Drug]]
[[Category: L-778,123]]
[[Category: L-778]]
[[Category: Lipid modification]]
[[Category: Lipid modification]]
[[Category: Protein geranylgeranyltransferase type-i]]
[[Category: Protein geranylgeranyltransferase type-i]]
[[Category: Protein prenylation]]
[[Category: Protein prenylation]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:35:48 2009''

Revision as of 10:31, 4 January 2013

File:1s64.png

Template:STRUCTURE 1s64

Rat protein geranylgeranyltransferase type-I complexed with L-778,123 and a sulfate anion

Template:ABSTRACT PUBMED 15248757

About this Structure

1s64 is a 12 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  1. Reid TS, Long SB, Beese LS. Crystallographic analysis reveals that anticancer clinical candidate L-778,123 inhibits protein farnesyltransferase and geranylgeranyltransferase-I by different binding modes. Biochemistry. 2004 Jul 20;43(28):9000-8. PMID:15248757 doi:10.1021/bi049280b

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