Sandbox Reserved 709: Difference between revisions
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Nup50 (''Nucleoporin 50 kDa'', about 450 aminoacids) is a part of the NPCs, in the nucleoplasmic side. It is able to bind to <scene name='Sandbox_Reserved_709/Importin/1'> importin α</scene>thanks to its <scene name='Sandbox_Reserved_709/Nup50/1'>N-terminal domain</scene> (''only represented on the structure''). There are two binding sites for Nup50 on importin α : | Nup50 (''Nucleoporin 50 kDa'', about 450 aminoacids) is a part of the NPCs, in the nucleoplasmic side. It is able to bind to <scene name='Sandbox_Reserved_709/Importin/1'> importin α</scene>thanks to its <scene name='Sandbox_Reserved_709/Nup50/1'>N-terminal domain</scene> (''only represented on the structure''). There are two binding sites for Nup50 on importin α : | ||
* The first one overlaps with the minor NLS binding site. The affinity of Nup50 for this site is... | * The first one overlaps with the minor NLS binding site. The affinity of Nup50 for this site is... <scene name='Sandbox_Reserved_709/Nup_bindingnls/1'>Lys3 and Arg4</scene> | ||
==See Also== | ==See Also== | ||
