1t2v: Difference between revisions

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{{Seed}}
[[Image:1t2v.png|left|200px]]
[[Image:1t2v.png|left|200px]]


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{{STRUCTURE_1t2v|  PDB=1t2v  |  SCENE=  }}  
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===Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide===
===Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide===


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{{ABSTRACT_PUBMED_15133503}}
{{ABSTRACT_PUBMED_15133503}}
==Disease==
Known disease associated with this structure: Breast cancer-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast-ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Papillary serous carcinoma of the peritoneum OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]]


==About this Structure==
==About this Structure==
1T2V is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2V OCA].  
[[1t2v]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2V OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15133503</ref><references group="xtra"/>
<ref group="xtra">PMID:015133503</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Glover, J N.M.]]
[[Category: Glover, J N.M.]]
Line 32: Line 17:
[[Category: Lee, M S.]]
[[Category: Lee, M S.]]
[[Category: Williams, R S.]]
[[Category: Williams, R S.]]
[[Category: Antitumor protein]]
[[Category: Brca1]]
[[Category: Brca1]]
[[Category: Brct]]
[[Category: Brct]]
Line 38: Line 24:
[[Category: Missense mutation]]
[[Category: Missense mutation]]
[[Category: Phosphopeptide]]
[[Category: Phosphopeptide]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:57:16 2009''

Revision as of 11:43, 5 January 2013

File:1t2v.png

Template:STRUCTURE 1t2v

Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide

Template:ABSTRACT PUBMED 15133503

About this Structure

1t2v is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Williams RS, Lee MS, Hau DD, Glover JN. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat Struct Mol Biol. 2004 Jun;11(6):519-25. Epub 2004 May 9. PMID:15133503 doi:https://dx.doi.org/10.1038/nsmb776

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