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Revision as of 18:57, 5 January 2013 view source Pernelle Klein (talk \| contribs) 122 edits →'''Structure of the complex''' ← Older edit		Revision as of 18:59, 5 January 2013 view source Pernelle Klein (talk \| contribs) 122 edits →'''Structure of the complex''' Newer edit →
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	*The first contact area of the Rab27B/Slac2-a interface consists of residues 6–9 from the Rab complementarity-determining regions (RabCDR) , part of the switch and interswitch regions of Rab27B, and the coiled-coil regions of Slac2-a.<ref>PMID:18940604</ref> In this first contact area we can find three different types of ~~interaction~~, electrostatic, hydrophobic and hydrogen bonds: (also see figure 3A)		*The first contact area of the Rab27B/Slac2-a interface consists of residues 6–9 from the Rab complementarity-determining regions (RabCDR) , part of the switch and interswitch regions of Rab27B, and the coiled-coil regions of Slac2-a.<ref>PMID:18940604</ref> In this first contact area we can find three different types of interactions, electrostatic, hydrophobic and hydrogen bonds: (also see figure 3A)

	**Phe81, Leu84, and Phe88 from switch 2 of Rab27B participate in hydrophobic interactions with the residues from α1 and α5 of Slac2-a.		**Phe81, Leu84, and Phe88 from switch 2 of Rab27B participate in hydrophobic interactions with the residues from α1 and α5 of Slac2-a.

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