1v1f: Difference between revisions

Line 4:

==Overview==

The Arabidopsis thaliana SOS3 gene encodes a calcium sensor that is, required for plant salt tolerance. The SOS3 protein binds to and activates, the self-inhibited SOS2 protein kinase, which mediates the expression and, activities of various transporters important for ion homeostasis under, salt stress. SOS3 belongs to a unique family of calcium-binding proteins, that contain two pairs of EF hand motifs with four putative metal-binding, sites. We report the crystal structure of a dimeric SOS3 protein in, complex with calcium, and with calcium and manganese. Analytical, ultracentrifugation experiments and circular dichroism measurements show, that calcium binding is responsible for the dimerization of SOS3. This, leads to a change in the global shape and surface properties of the, protein that may be sufficient to transmit the Ca(2+) signal elicited, during salt stress.

The Arabidopsis thaliana SOS3 gene encodes a calcium sensor that is required for plant salt tolerance. The SOS3 protein binds to and activates the self-inhibited SOS2 protein kinase, which mediates the expression and activities of various transporters important for ion homeostasis under salt stress. SOS3 belongs to a unique family of calcium-binding proteins that contain two pairs of EF hand motifs with four putative metal-binding sites. We report the crystal structure of a dimeric SOS3 protein in complex with calcium, and with calcium and manganese. Analytical ultracentrifugation experiments and circular dichroism measurements show that calcium binding is responsible for the dimerization of SOS3. This leads to a change in the global shape and surface properties of the protein that may be sufficient to transmit the Ca(2+) signal elicited during salt stress.

==About this Structure==

Line 15:

[[Category: Albert, A.]]

[[Category: Martinez-Ripoll, M.]]

[[Category: Sanchez-Barrena, M.J.]]

[[Category: Sanchez-Barrena, M J.]]

[[Category: Zhu, J.K.]]

[[Category: Zhu, J K.]]

[[Category: CA]]

[[Category: IOD]]

Line 28:

[[Category: signalling protein]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun~~ Feb ~~3 10~~:16:46 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:30:31 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 4: / Line 4: @@
 ==Overview==
-The Arabidopsis thaliana SOS3 gene encodes a calcium sensor that is, required for plant salt tolerance. The SOS3 protein binds to and activates, the self-inhibited SOS2 protein kinase, which mediates the expression and, activities of various transporters important for ion homeostasis under, salt stress. SOS3 belongs to a unique family of calcium-binding proteins, that contain two pairs of EF hand motifs with four putative metal-binding, sites. We report the crystal structure of a dimeric SOS3 protein in, complex with calcium, and with calcium and manganese. Analytical, ultracentrifugation experiments and circular dichroism measurements show, that calcium binding is responsible for the dimerization of SOS3. This, leads to a change in the global shape and surface properties of the, protein that may be sufficient to transmit the Ca(2+) signal elicited, during salt stress.
+The Arabidopsis thaliana SOS3 gene encodes a calcium sensor that is required for plant salt tolerance. The SOS3 protein binds to and activates the self-inhibited SOS2 protein kinase, which mediates the expression and activities of various transporters important for ion homeostasis under salt stress. SOS3 belongs to a unique family of calcium-binding proteins that contain two pairs of EF hand motifs with four putative metal-binding sites. We report the crystal structure of a dimeric SOS3 protein in complex with calcium, and with calcium and manganese. Analytical ultracentrifugation experiments and circular dichroism measurements show that calcium binding is responsible for the dimerization of SOS3. This leads to a change in the global shape and surface properties of the protein that may be sufficient to transmit the Ca(2+) signal elicited during salt stress.
 ==About this Structure==
@@ Line 15: / Line 15: @@
 [[Category: Albert, A.]]
 [[Category: Martinez-Ripoll, M.]]
-[[Category: Sanchez-Barrena, M.J.]]
+[[Category: Sanchez-Barrena, M J.]]
-[[Category: Zhu, J.K.]]
+[[Category: Zhu, J K.]]
 [[Category: CA]]
 [[Category: IOD]]
@@ Line 28: / Line 28: @@
 [[Category: signalling protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb  3 10:16:46 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:30:31 2008''