2aow: Difference between revisions

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{{Seed}}
[[Image:2aow.png|left|200px]]
[[Image:2aow.png|left|200px]]


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{{STRUCTURE_2aow|  PDB=2aow  |  SCENE=  }}  
{{STRUCTURE_2aow|  PDB=2aow  |  SCENE=  }}  


===Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine===
===Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine===


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{{ABSTRACT_PUBMED_16168438}}
{{ABSTRACT_PUBMED_16168438}}
==Disease==
Known disease associated with this structure: Asthma, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=605238 605238]]


==About this Structure==
==About this Structure==
2AOW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOW OCA].  
[[2aow]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOW OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:16168438</ref><references group="xtra"/>
<ref group="xtra">PMID:016168438</ref><references group="xtra"/>
[[Category: Histamine N-methyltransferase]]
[[Category: Histamine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 35: Line 20:
[[Category: Classic methyltransferase fold]]
[[Category: Classic methyltransferase fold]]
[[Category: Protein-drug complex]]
[[Category: Protein-drug complex]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:45:55 2009''

Revision as of 10:41, 6 January 2013

File:2aow.png

Template:STRUCTURE 2aow

Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine

Template:ABSTRACT PUBMED 16168438

About this Structure

2aow is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Horton JR, Sawada K, Nishibori M, Cheng X. Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. J Mol Biol. 2005 Oct 21;353(2):334-44. PMID:16168438 doi:10.1016/j.jmb.2005.08.040

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