2auh: Difference between revisions

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{{Seed}}
[[Image:2auh.png|left|200px]]
[[Image:2auh.png|left|200px]]


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{{STRUCTURE_2auh|  PDB=2auh  |  SCENE=  }}  
{{STRUCTURE_2auh|  PDB=2auh  |  SCENE=  }}  


===Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase===
===Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase===


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{{ABSTRACT_PUBMED_16246733}}
{{ABSTRACT_PUBMED_16246733}}


==Disease==
==About this Structure==
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]]
[[2auh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AUH OCA].  


==About this Structure==
==See Also==
2AUH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AUH OCA].
*[[Insulin receptor|Insulin receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:16246733</ref><references group="xtra"/>
<ref group="xtra">PMID:016246733</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Transferase]]
[[Category: Transferase]]
Line 36: Line 24:
[[Category: Hubbard, S R.]]
[[Category: Hubbard, S R.]]
[[Category: Bps region]]
[[Category: Bps region]]
[[Category: Transferase/signaling protein complex]]
[[Category: Transferase-signaling protein complex]]
[[Category: Tyrosine kinase]]
[[Category: Tyrosine kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:39:19 2009''

Revision as of 10:59, 6 January 2013

File:2auh.png

Template:STRUCTURE 2auh

Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase

Template:ABSTRACT PUBMED 16246733

About this Structure

2auh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Depetris RS, Hu J, Gimpelevich I, Holt LJ, Daly RJ, Hubbard SR. Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14. Mol Cell. 2005 Oct 28;20(2):325-33. PMID:16246733 doi:10.1016/j.molcel.2005.09.001

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