2cem: Difference between revisions

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Revision as of 11:48, 6 January 2013

File:2cem.png

Template:STRUCTURE 2cem

P1' EXTENDED HIV-1 PROTEASE INHIBITORS ENCOMPASSING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMICKING SCAFFOLD

Template:ABSTRACT PUBMED 16509598

About this Structure

2cem is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Ekegren JK, Ginman N, Johansson A, Wallberg H, Larhed M, Samuelsson B, Unge T, Hallberg A. Microwave-accelerated synthesis of P1'-extended HIV-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold. J Med Chem. 2006 Mar 9;49(5):1828-32. PMID:16509598 doi:10.1021/jm051239z

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