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{{Seed}}
[[Image:2aoc.png|left|200px]]
[[Image:2aoc.png|left|200px]]


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{{STRUCTURE_2aoc|  PDB=2aoc  |  SCENE=  }}  
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===Crystal structure analysis of HIV-1 protease mutant I84V with a substrate analog P2-NC===
===Crystal structure analysis of HIV-1 protease mutant I84V with a substrate analog P2-NC===


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{{ABSTRACT_PUBMED_16218957}}
{{ABSTRACT_PUBMED_16218957}}


==About this Structure==
==About this Structure==
2AOC is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOC OCA].  
[[2aoc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(bh5_isolate) Human immunodeficiency virus type 1 (bh5 isolate)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOC OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:16218957</ref><references group="xtra"/>
<ref group="xtra">PMID:016218957</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Boross, P I.]]
[[Category: Boross, P I.]]
[[Category: Chen, X.]]
[[Category: Chen, X.]]
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[[Category: Dimer]]
[[Category: Dimer]]
[[Category: Hiv-1 protease]]
[[Category: Hiv-1 protease]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Mutant]]
[[Category: Mutant]]
[[Category: Substrate analog]]
[[Category: Substrate analog]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:01:36 2009''

Revision as of 12:15, 6 January 2013

File:2aoc.png

Template:STRUCTURE 2aoc

Crystal structure analysis of HIV-1 protease mutant I84V with a substrate analog P2-NC

Template:ABSTRACT PUBMED 16218957

About this Structure

2aoc is a 2 chain structure with sequence from Human immunodeficiency virus type 1 (bh5 isolate). Full crystallographic information is available from OCA.

Reference

  1. Tie Y, Boross PI, Wang YF, Gaddis L, Liu F, Chen X, Tozser J, Harrison RW, Weber IT. Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs. FEBS J. 2005 Oct;272(20):5265-77. PMID:16218957 doi:10.1111/j.1742-4658.2005.04923.x

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