Sandbox Reserved 702: Difference between revisions

Line 78:

The edema factor has a 30 kDa protective antigen-binding domain at its <scene name='Sandbox_Reserved_702/Coloration_from_n_to_c_term/1'>N-terminus.</scene> ~~(shown in blue)~~

The edema factor has a 30 kDa protective antigen-binding domain at its <scene name='Sandbox_Reserved_702/Coloration_from_n_to_c_term/1'>N-terminus.</scene>

This domain exposes a richly negative-charged surface which easily interacts with the positively charged residues of the protective antigen. Edema factor's protective antigen-binding domain can be divided into two subdomains. ~~The N-terminal domain is composed of three layers, α/β sandwich domain (four β-sheets β1 to β4, in sandwich between four α-helices α1 to α4). The C-terminal domain is composed of five helices.~~ <scene name='Sandbox_Reserved_702/Secondary_structure/1'>~~See the secondary~~ structure.</scene> {{Template:ColorKey_Helix}},

The coloration is made according to this scheme: {{Template:ColorKey_N2CRainbow}}

This domain exposes a richly negative-charged surface which easily interacts with the positively charged residues of the protective antigen. Edema factor's protective antigen-binding domain can be divided into two subdomains.

<scene name='Sandbox_Reserved_702/Secondary_structure/1'>Secondary structure of 1lvc.</scene> {{Template:ColorKey_Helix}},

{{Template:ColorKey_Strand}}.

The N-terminal domain is composed of three layers, α/β sandwich domain (four β-sheets β1 to β4, in sandwich between four α-helices α1 to α4). The C-terminal domain is composed of five helices.

The protective antigen-binding domain contains five joining loops L1 to L5, and L5 has the key exposed residues that bind to the protective antigen. Residues in α6, α7 and in the joining loop between α7 and α8 at the C-terminal domain are also implied in the interaction. <ref> PMID: 15719022</ref>

Sandbox Reserved 702: Difference between revisions

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@@ Line 78: / Line 78: @@
 <Structure load='1lvc' size='500' frame='true' align='right' caption='1lvc'/>
-The edema factor has a 30 kDa protective antigen-binding domain at its <scene name='Sandbox_Reserved_702/Coloration_from_n_to_c_term/1'>N-terminus.</scene> (shown in blue)
+The edema factor has a 30 kDa protective antigen-binding domain at its <scene name='Sandbox_Reserved_702/Coloration_from_n_to_c_term/1'>N-terminus.</scene>
-This domain exposes a richly negative-charged surface which easily interacts with the positively charged residues of the protective antigen. Edema factor's protective antigen-binding domain can be divided into two subdomains. The N-terminal domain is composed of three layers, α/β sandwich domain (four β-sheets β1 to β4, in sandwich between four α-helices α1 to α4). The C-terminal domain is composed of five helices. <scene name='Sandbox_Reserved_702/Secondary_structure/1'>See the secondary structure.</scene> {{Template:ColorKey_Helix}},
+The coloration is made according to this scheme: {{Template:ColorKey_N2CRainbow}}
+This domain exposes a richly negative-charged surface which easily interacts with the positively charged residues of the protective antigen. Edema factor's protective antigen-binding domain can be divided into two subdomains.
+<scene name='Sandbox_Reserved_702/Secondary_structure/1'>Secondary structure of 1lvc.</scene> {{Template:ColorKey_Helix}},
 {{Template:ColorKey_Strand}}.
+The N-terminal domain is composed of three layers, α/β sandwich domain (four β-sheets β1 to β4, in sandwich between four α-helices α1 to α4). The C-terminal domain is composed of five helices.
 The protective antigen-binding domain contains five joining loops L1 to L5, and L5 has the key exposed residues that bind to the protective antigen. Residues in α6, α7 and in the joining loop between α7 and α8 at the C-terminal domain are also implied in the interaction. <ref> PMID: 15719022</ref>