Sandbox Reserved 706: Difference between revisions

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There are three contact areas in the interface between Rab27B and Slac2-a.  The first and second contact areas involve the coiled-coil regions of Slac2-a and constitute the main interface.
There are three contact areas in the interface between Rab27B and Slac2-a.  The first and second contact areas involve the coiled-coil regions of Slac2-a and constitute the main interface.
[[Image:Rab27B slac2a image3.gif | 200 px | thumb | left |Picture 4: Rab27B/Slac2-a contact interfaces :
[[Image:Rab27B slac2a image3.gif | 200 px | thumb | left |Picture 4: Rab27B/Slac2-a contact interfaces :
(A) Contact area 1  
(A) Contact area 1,
(C) Contact area 2  
(C) Contact area 2,
(E) Contact area 3.
(E) Contact area 3.]]
  ]]
 
*The first contact area of the Rab27B/Slac2-a interface consists of <scene name='Sandbox_Reserved_706/6a9_rabcdr/2'> residues 6 to 9 from  the Rab complementarity-determining regions (RabCDR)</scene> , part of the switch and interswitch regions of Rab27B, and the coiled-coil regions of Slac2-a.<ref>PMID:18940604</ref> In this first contact area we can find three different types of interactions, electrostatic, hydrophobic and hydrogen bonds: (see figure 4A)
*The first contact area of the Rab27B/Slac2-a interface consists of <scene name='Sandbox_Reserved_706/6a9_rabcdr/2'> residues 6 to 9 from  the Rab complementarity-determining regions (RabCDR)</scene> , part of the switch and interswitch regions of Rab27B, and the coiled-coil regions of Slac2-a.<ref>PMID:18940604</ref> In this first contact area we can find three different types of interactions, electrostatic, hydrophobic and hydrogen bonds: (see figure 4A)