2o5d: Difference between revisions

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{{Seed}}
[[Image:2o5d.png|left|200px]]
[[Image:2o5d.png|left|200px]]


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{{STRUCTURE_2o5d|  PDB=2o5d  |  SCENE=  }}  
{{STRUCTURE_2o5d|  PDB=2o5d  |  SCENE=  }}  


===Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study===
===Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study===


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{{ABSTRACT_PUBMED_17276060}}
{{ABSTRACT_PUBMED_17276060}}


==About this Structure==
==About this Structure==
2O5D is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5D OCA].  
[[2o5d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5D OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:17276060</ref><references group="xtra"/>
<ref group="xtra">PMID:017276060</ref><references group="xtra"/>
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
Line 33: Line 21:
[[Category: Rdrp]]
[[Category: Rdrp]]
[[Category: Structure-based drug design]]
[[Category: Structure-based drug design]]
[[Category: Viral protein]]
[[Category: Viral rna-directed rna polymerase]]
[[Category: Viral rna-directed rna polymerase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:06:27 2009''

Revision as of 10:39, 7 January 2013

File:2o5d.png

Template:STRUCTURE 2o5d

Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: Convergence of structure-based drug design and X-ray crystallographic study

Template:ABSTRACT PUBMED 17276060

About this Structure

2o5d is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  1. Yan S, Appleby T, Larson G, Wu JZ, Hamatake RK, Hong Z, Yao N. Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: convergence of structure-based drug design and X-ray crystallographic study. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1991-5. Epub 2007 Jan 19. PMID:17276060 doi:10.1016/j.bmcl.2007.01.024

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