2hs2: Difference between revisions

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Revision as of 10:44, 7 January 2013

File:2hs2.png

Template:STRUCTURE 2hs2

Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir)

Template:ABSTRACT PUBMED 16962136

About this Structure

2hs2 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136 doi:10.1016/j.jmb.2006.08.007

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