2gll: Difference between revisions

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Revision as of 10:51, 7 January 2013

File:2gll.png

Template:STRUCTURE 2gll

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase(FabZ) from Helicobacter pylori

Template:ABSTRACT PUBMED 18093984

About this Structure

2gll is a 6 chain structure with sequence from Helicobacter pylori. Full crystallographic information is available from OCA.

Reference

  1. Zhang L, Liu W, Hu T, Du L, Luo C, Chen K, Shen X, Jiang H. Structural basis for catalytic and inhibitory mechanisms of beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ). J Biol Chem. 2008 Feb 29;283(9):5370-9. Epub 2007 Dec 19. PMID:18093984 doi:10.1074/jbc.M705566200
  2. He L, Zhang L, Liu X, Li X, Zheng M, Li H, Yu K, Chen K, Shen X, Jiang H, Liu H. Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. J Med Chem. 2009 Apr 23;52(8):2465-81. PMID:19309082 doi:10.1021/jm8015602

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