2prl: Difference between revisions
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[[Image:2prl.png|left|200px]] | [[Image:2prl.png|left|200px]] | ||
{{STRUCTURE_2prl| PDB=2prl | SCENE= }} | {{STRUCTURE_2prl| PDB=2prl | SCENE= }} | ||
===The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site=== | ===The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site=== | ||
{{ABSTRACT_PUBMED_18672895}} | {{ABSTRACT_PUBMED_18672895}} | ||
==About this Structure== | ==About this Structure== | ||
[[2prl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PRL OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018672895</ref><references group="xtra"/> | ||
[[Category: Dihydroorotate dehydrogenase]] | [[Category: Dihydroorotate dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Protein inhibitor complex]] | [[Category: Protein inhibitor complex]] | ||
Revision as of 10:59, 7 January 2013
The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site
Template:ABSTRACT PUBMED 18672895
About this Structure
2prl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Walse B, Dufe VT, Svensson B, Fritzson I, Dahlberg L, Khairoullina A, Wellmar U, Al-Karadaghi S. The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites. Biochemistry. 2008 Aug 26;47(34):8929-36. Epub 2008 Aug 2. PMID:18672895 doi:10.1021/bi8003318
