2hr7: Difference between revisions

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{{Seed}}
[[Image:2hr7.png|left|200px]]
[[Image:2hr7.png|left|200px]]


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{{STRUCTURE_2hr7|  PDB=2hr7  |  SCENE=  }}  
{{STRUCTURE_2hr7|  PDB=2hr7  |  SCENE=  }}  


===Insulin receptor (domains 1-3)===
===Insulin receptor (domains 1-3)===


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{{ABSTRACT_PUBMED_16894147}}
{{ABSTRACT_PUBMED_16894147}}


==Disease==
==About this Structure==
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]]
[[2hr7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HR7 OCA].  


==About this Structure==
==See Also==
2HR7 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HR7 OCA].
*[[Insulin receptor|Insulin receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:16894147</ref><references group="xtra"/>
<ref group="xtra">PMID:016894147</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Leucine rich repeat]]
[[Category: Leucine rich repeat]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:25:23 2009''

Revision as of 10:59, 7 January 2013

File:2hr7.png

Template:STRUCTURE 2hr7

Insulin receptor (domains 1-3)

Template:ABSTRACT PUBMED 16894147

About this Structure

2hr7 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Lou M, Garrett TP, McKern NM, Hoyne PA, Epa VC, Bentley JD, Lovrecz GO, Cosgrove LJ, Frenkel MJ, Ward CW. The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12429-34. Epub 2006 Aug 7. PMID:16894147

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