Sandbox 719: Difference between revisions
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Zoé Blanck (talk | contribs) |
Zoé Blanck (talk | contribs) |
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==== The tetramer Interface ==== | ==== The tetramer Interface ==== | ||
[[Image:Tetramer-interface.jpg]] | |||
The most striking feature of DsRed is that, as shown in Fig. 2, it exists as an extremely close-packed tetramer, quite unlike the primarily monomeric avGFP. The tetramer is a square prism with remarkably flat sides and a small elliptical hole directly through the center. The hole is lined with polar residues and salt bridges and localizes a number of solvent molecules. | The most striking feature of DsRed is that, as shown in Fig. 2, it exists as an extremely close-packed tetramer, quite unlike the primarily monomeric avGFP. The tetramer is a square prism with remarkably flat sides and a small elliptical hole directly through the center. The hole is lined with polar residues and salt bridges and localizes a number of solvent molecules. | ||
The accessible surface area of the isolated monomer (21) is 10,230 Å2, and that of the tetramer is 31,420 Å2, so roughly 25% of the monomer surface is not solvent accessible in the tetramer. | The accessible surface area of the isolated monomer (21) is 10,230 Å2, and that of the tetramer is 31,420 Å2, so roughly 25% of the monomer surface is not solvent accessible in the tetramer. | ||
